Programme

Unfurtunately the monastery Irsee has been closed by the Bavarian government due to the corona virus.

Therefore we have decided to offer the conference as a web conference only.

In those unpredictable times, protecting our participants’ health has the highest priority for us!

The scientific exchange must not come to a complete standstill and we believe that with this web solution we have found a way to keep the scientific community going.

In order to participate in the livestream of the conference as easy as possible and to give your presentation, we recommend the use of the web browsers Google Chrome or Microsoft Edge.

Here you can find detailed instructions for using the livestream.

As a participant of the Bioinspired 2020 you have received an e-mail containing the login data for the web conference.

The login data for the sessions are provided daily.

In order to allow all conference participants access to the posters, we ask you to upload your poster by login on the conference homepage and clicking on the button "My Submission" in the upper right corner of the conference homepage. Then select the submission to which you want to upload the poster and upload the poster at the bottom of the page.

Furthermore we would like to ask all poster authors to prepare 4 PowerPoint slides to present your poster to the audience.
Please also include your contact details on the digital poster to allow participants to reach you with questions.

Please note that your poster will be pictured publically.

As poster author you can upload your poster similar to the way you submitted your abstract.
Click on "My Submissions" in the upper right corner at the homepage.

Poster documents can be found by opening the respective abstract in the online programme.
If a poster document has already been uploaded for the abstract, it can then be opened and downloaded.

Please note that your poster will be pictured publically.

You can ask your questions via chat already during the presentations!
Please use for this the Q&A (F&A) button!

For further scientific exchange we implemented a discussion forum on the homepage of the DGM.
Please visit discussion.dgm.de and use your DGM or Bioinspired user credentials to login.

Back to overview

Special Poster Session Biofabrication

Simultaneous printing of skeletal muscle tissue models and customized bioreactor

Tuesday (17.03.2020)
18:10 - 18:13

Biofabrication of personalized tissues using 3D printing techniques is a new approach which is revolutionizing the field of tissue engineering. Replacement of injured tissues usually faces issues like donor tissue availability and immune rejection of the transplanted tissue. Fabrication and maturation of a functional tissue under in vitro conditions seems possible using bioprinting of the tissue within a printed bioreactor. Combination of these steps will take us one step closer to personalized treatment.

To achieve this, a bioink based on alginate-di-aldehyde (ADA) and gelatin was designed. Schiff’s base bonds between ADA and gelatin as well as temperature dependent crosslinking ensures multilayer bioprintability.

Complexity and maturation of artificial tissues are essential for proper tissue function. To ensure this, biological and technical approaches were combined. High density of skeletal muscle cells (C2C12) were mixed with the bioink and prealigned during the printing system under applied shear forces. In addition a customized bioreactor was designed that simulates in vivo-like dynamic flow conditions to the printed muscle construct. Therefore, first a porous, lignin based tissue container was printed. Bioprinting the cell containing bioink was performed inside the printed container. After printing, the tissue container was sealed by a silicone housing and connected to a dynamic media flow system. Maintaining this condition for at least one week has shown cell proliferation and tissue maturation.

Speaker:
Dipl.-Ing. Claudia Müller
University of Bayreuth
Additional Authors:
  • Marius Gensler
    University Hospital Würzburg
  • Susanne Heid
    Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
  • Prof. Dr. Aldo R. Boccaccini
    Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
  • Dr. Rainer Detsch
    Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
  • Prof. Dr. Jan Hansmann
    University Hospital Würzburg
  • Dr. Sahar Salehi
    Universität Bayreuth