Programme

Unfurtunately the monastery Irsee has been closed by the Bavarian government due to the corona virus.

Therefore we have decided to offer the conference as a web conference only.

In those unpredictable times, protecting our participants’ health has the highest priority for us!

The scientific exchange must not come to a complete standstill and we believe that with this web solution we have found a way to keep the scientific community going.

In order to participate in the livestream of the conference as easy as possible and to give your presentation, we recommend the use of the web browsers Google Chrome or Microsoft Edge.

Here you can find detailed instructions for using the livestream.

As a participant of the Bioinspired 2020 you have received an e-mail containing the login data for the web conference.

The login data for the sessions are provided daily.

In order to allow all conference participants access to the posters, we ask you to upload your poster by login on the conference homepage and clicking on the button "My Submission" in the upper right corner of the conference homepage. Then select the submission to which you want to upload the poster and upload the poster at the bottom of the page.

Furthermore we would like to ask all poster authors to prepare 4 PowerPoint slides to present your poster to the audience.
Please also include your contact details on the digital poster to allow participants to reach you with questions.

Please note that your poster will be pictured publically.

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Click on "My Submissions" in the upper right corner at the homepage.

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Back to overview

Poster with short presentation

Biomimetic nuclear lamin fibers with very high toughness and stiffness

Monday (16.03.2020)
17:44 - 17:47

In nature, the mechanical properties of fibers based on -helical coiled-coil proteins, such as intermediate filament (IF)-proteins, are found between the soft and stretchable elastin and the highly tough and stiff dragline spider silks. Although spider silks have been the focus of many biomimetic studies in recent decades, the design of artificial IF-protein-based fibers has scarcely been studied. The work presented here demonstrates that the recombinant C. elegans (Ce-) lamin, type V IF-protein that constitutes a major component of the nuclear lamina, can be solubilized in and wet-spun into aqueous solutions to produce fibers with a toughness of 150±40 MJ/m3 and a stiffness of 8.4±1.5 GPa but without using chemical crosslinkers. Thus, the Ce-lamin is the first recombinant protein that simultaneously achieves the toughness and stiffness of natural dragline spider silks, the toughest fibers in nature. We posit that the source of the fiber’s stiffness and high toughness is a specific structural organization of Ce-lamin tetramers into paracrystal networks (typical Ce-lamin higher order structures). Raman analysis of drawn and non-drawn fibers showed that enrichment of -sheet structures during the long plastic deformation might be an additional factor for the high toughness. This work demonstrates that certain organizations of recombinant IF-proteins can result in fibers that exhibit outstanding mechanical properties, thus broadening the pool of fibrous proteins that can be used in functional materials across a diverse range of applications.

Speaker:
Dr. Kfir Ben-Harush
Shamoon College of Engineering (SCE)
Additional Authors:
  • Maayan Khayat
    Shamoon College of Engineering (SCE)
  • Shani Deri
    Shamoon College of Engineering (SCE)
  • Dr. Tom Trigano
    Shamoon College of Engineering (SCE)
  • Prof. David Wolf
    Ariel University
  • Prof. Ohad Medalia
    University of Zurich